load datasets

Now let’s focus on samples with genotype data.

      PTSD_diagnosis
sex       0    1 2092 7011
  0    1300  552    0    0
  1    3517 1631    0    0
  519     0    0    1    0
  8584    0    0    0    1
  • What is a better trauma exposure measure we should use?
  • Do we have CRP and other molecular markers measured?
  • Do we have BMI and other anthropometric measurements?

Controls (N=3902) Cases (N=1813) Total (N=5715) p value
PSStotal < 0.001
   Mean (SD) 6.288 (6.773) 26.763 (9.411) 12.784 (12.256)
   Range 0.000 - 47.000 4.250 - 51.000 0.000 - 51.000
BDItotalscore < 0.001
   N-Miss 134 85 219
   Mean (SD) 9.864 (9.222) 24.037 (11.890) 14.320 (12.085)
   Range 0.000 - 63.000 0.000 - 59.000 0.000 - 63.000
as.factor(BDI_CAT) < 0.001
   N-Miss 134 85 219
   0 3168 (84.1%) 627 (36.3%) 3795 (69.1%)
   1 600 (15.9%) 1101 (63.7%) 1701 (30.9%)
age 0.458
   N-Miss 16 13 29
   Mean (SD) 39.927 (14.319) 40.219 (12.564) 40.020 (13.787)
   Range 18.000 - 78.000 18.000 - 70.000 18.000 - 78.000
as.factor(sex) 0.080
   N-Miss 7 3 10
   0 1034 (26.5%) 441 (24.4%) 1475 (25.9%)
   1 2861 (73.5%) 1369 (75.6%) 4230 (74.1%)
education 0.072
   N-Miss 20 18 38
   Mean (SD) 1.887 (1.639) 1.803 (1.620) 1.860 (1.633)
   Range 0.000 - 6.000 0.000 - 6.000 0.000 - 6.000
CTQTOT < 0.001
   N-Miss 30 15 45
   Mean (SD) 36.651 (14.087) 49.652 (20.422) 40.774 (17.445)
   Range 25.000 - 112.500 25.000 - 125.000 25.000 - 125.000
as.factor(race_ethnic) < 0.001
   N-Miss 16 18 34
   0 3655 (94.1%) 1633 (91.0%) 5288 (93.1%)
   1 25 (0.6%) 16 (0.9%) 41 (0.7%)
   2 6 (0.2%) 1 (0.1%) 7 (0.1%)
   3 105 (2.7%) 77 (4.3%) 182 (3.2%)
   4 52 (1.3%) 47 (2.6%) 99 (1.7%)
   5 43 (1.1%) 21 (1.2%) 64 (1.1%)
Controls
(N=3902)		 Cases
(N=1813)		 Overall
(N=5715)
PSStotal
Mean (SD) 6.29 (6.77) 26.8 (9.41) 12.8 (12.3)
Median [Min, Max] 4.00 [0, 47.0] 26.0 [4.25, 51.0] 9.00 [0, 51.0]
BDItotalscore
Mean (SD) 9.86 (9.22) 24.0 (11.9) 14.3 (12.1)
Median [Min, Max] 7.35 [0, 63.0] 23.0 [0, 59.0] 11.0 [0, 63.0]
Missing 134 (3.4%) 85 (4.7%) 219 (3.8%)
Age
Mean (SD) 39.9 (14.3) 40.2 (12.6) 40.0 (13.8)
Median [Min, Max] 41.0 [18.0, 78.0] 42.0 [18.0, 70.0] 41.0 [18.0, 78.0]
Missing 16 (0.4%) 13 (0.7%) 29 (0.5%)
as.factor(sex)
0 1034 (26.5%) 441 (24.3%) 1475 (25.8%)
1 2861 (73.3%) 1369 (75.5%) 4230 (74.0%)
Missing 7 (0.2%) 3 (0.2%) 10 (0.2%)
education
Mean (SD) 1.89 (1.64) 1.80 (1.62) 1.86 (1.63)
Median [Min, Max] 1.00 [0, 6.00] 1.00 [0, 6.00] 1.00 [0, 6.00]
Missing 20 (0.5%) 18 (1.0%) 38 (0.7%)
Childhood trauma score
Mean (SD) 36.7 (14.1) 49.7 (20.4) 40.8 (17.4)
Median [Min, Max] 31.0 [25.0, 113] 45.0 [25.0, 125] 34.0 [25.0, 125]
Missing 30 (0.8%) 15 (0.8%) 45 (0.8%)
as.factor(race_ethnic)
0 3655 (93.7%) 1633 (90.1%) 5288 (92.5%)
1 25 (0.6%) 16 (0.9%) 41 (0.7%)
2 6 (0.2%) 1 (0.1%) 7 (0.1%)
3 105 (2.7%) 77 (4.2%) 182 (3.2%)
4 52 (1.3%) 47 (2.6%) 99 (1.7%)
5 43 (1.1%) 21 (1.2%) 64 (1.1%)
Missing 16 (0.4%) 18 (1.0%) 34 (0.6%)

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